Thbs2 gene

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August undefined, 2024

Web7 Mar 2024 · This study aims to investigate thrombospondin 2 (TSP2) expression levels in gastric cancer (GC) and determine the relationship between TSP2 and clinical characteristics and prognosis. The online database Gene Expression Profile Interactive Analysis (GEPIA) was used to analyse TSP2 mRNA expression levels in GC. The … WebTHBS2, TSP2. Gene ID (Human) 7058. Gene symbol. THBS2. UniProt ID (Human) P35442. Show Less . About This Kit. Human Thrombospondin-2 quantitates human Thrombospondin-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Thrombospondin-2.

THBS2 is a Potential Prognostic Biomarker in Colorectal Cancer

Web15 Jun 2024 · Another example includes a loop surrounding the Thbs2 gene (Fig. 4g). Similar to Adcyap1 , the Thbs2 gene is also an anxiety-related gene 41 that has an oestrogen response element in the promoter ... officer flips girl in desk

Differential Expression Pattern of THBS1 and THBS2 in …

Web21 Mar 2024 · The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. WebThe PCNT gene provides instructions for making a protein called pericentrin. Within cells, this protein is located in structures called centrosomes. Centrosomes play a role in cell division and the assembly of microtubules. Microtubules are fibers that help cells maintain their shape, assist in the process of cell division, and are essential ... Web29 Mar 2024 · General gene information Markers Homology Homologs of the THBS2 gene: The THBS2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, … officer flint 3d model

PUREE: accurate pan-cancer tumor purity estimation from gene …

THBS2 is Closely Related to the Poor Prognosis and …

Web22 Jan 2024 · Thbs2 thrombospondin 2 [ (house mouse)] Gene ID: 21826, updated on 22-Jan-2024 Summary Predicted to enable calcium ion binding activity and heparin binding … Web28 Sep 2014 · Background Thrombospondins (THBSs) are a family of multidomain and secreted matricellular Ca2+-binding glycoproteins which has at least five members encoded by independent genes. As a THBSs family member, Thrombospondin2 (THBS2) has been reported to regulate angiogenesis. Nevertheless, the functions and clinical significance of … officer flint vrchat avatarhttp://www.cancerindex.org/geneweb/THBS2.htm my dentist blackburn reviews

"Web11 Apr 2024 · The gene expression data and the cell type labels of the head and neck cancer single-cell cohort used in the feature set validation was taken from the publication by Tirosh et al. (Gene Expression ... " - Thbs2 gene

Thbs2 gene

http://www.cancerindex.org/geneweb/THBS2.htm Web16 Sep 2016 · Interestingly, combination the average of top 20 genes and THBS2 showed a higher risk in overall survival (p < 0.001, 2.890(1.676–4.981)) than the average of top 20 …

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Web20 Dec 2006 · Of the 5 thrombospondin genes, only THBS2, THBS4, and COMP met the criteria for minimum detectable expression in at least one of these regions. In the array data, COMP had equivalent expression levels in the different brain regions of both species. WebTHBS2 - thrombospondin 2. The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis.

Web11 Aug 2016 · Thrombospondin 1 and thrombospondin 2 (THBS1 and THBS2) share similar multifunctional domains, and are known to be antiangiogenic. However, the expression … WebResults Based on bioinformatics analyses, THBS2 (FC: 7.14, FDR < 0.0001) has a significantly high expression in GC samples. lncRNAs BAIAP2-AS1, TSIX, and LINC01215 have RNA interaction with THBS2.

Web4 Apr 2024 · THBS2-positive group had markedly higher proportion of tumor diameter ≥ 2 cm, stage III–IV, lymph-node metastasis and high differentiation than THBS2-negative group (P < 0.01). WebThe expression of CD24 gene had a positive correlation with the expressions of thrombospondin 2 (THBS2) (r(s)=0.26, P<0.05), and had a negative correlation with the expression of epidermal growth factor containing fibulin like extracellular matrix protein 1 (EFEMP1), mesothelin (MSLN) and calbindin 2 (CALB2) (r(s)=-0.31, -0.52, -0.43, P<0.05 ...

Web24 Jun 2024 · The genetic and protein expression of THBS2 in CRC were explored across several databases, including ONCOMINE, GEPIA2, TIMER 2.0, UALCAN and HPA …

Web10 Jun 2008 · HGNC Approved Gene Symbol: THBS2 Cytogenetic location: 6q27 Genomic coordinates (GRCh38): 6:169,215,785-169,253,846 (from NCBI) Gene-Phenotype Relationships PheneGene Graphics TEXT Cloning and Expression Thrombospondin was originally discovered as a secretory product of platelet alpha-granules ( Baenziger et al., … officer floristWeb8 Jan 2024 · CytoHubba selected the top ten hub genes, which included SPP1, TIMP1, SERPINE1, MMP3, COL1A1, BGN, THBS2, CDH2, CXCL8, and THY1. With the exception of SPP1, survival analysis using the Kaplan–Meier database showed that the levels of expression of these genes were associated with overall survival. my dentist brinsworthWeb24 Jun 2024 · Group A Thbs proteins form trimers that consist of Thbs1 and Thbs2, while group B Thbs proteins form pentamers that consist of Thbs3, Thbs4, and Thbs5 11. … officer fmf pqsWeb22 Mar 2024 · THBS2 and the Wnt/β-catenin signaling pathway are known to be closely related in various cancers. 9 THBS2, a microRNA-744-5p target, modulates MMP-9 expression through CUX1 in pancreatic … officer foley gameWebGene locations. mm10 chr17:14665500-14694262; mm9 chr17:14802507-14831269 officer flint artWebGastric cancer (GC) is a kind of common cancer worldwide. Too late in diagnosis results in poor prognosis of patients with GC. Thrombospondin-2 (THBS2) is a type of secreted protein that has been found to be a diagnostic biomarker in a variety of cancers. Our study aimed to uncover the clinical value of THBS2 in early detection for patients with gastric cancer. … officer floyd east jrWebThe recent publication of a 10-gene biomarker panel generates new hope for the prognostication and personalization of therapy in ovarian cancer. Expression of the 10 biomarker genes (AEBP1, COL11A1, COL5A1, COL6A2, LOX, POSTN, SNAI2, THBS2, TIMP3, VCAN) in primary ovarian tumors correlates with metastasis, recurrence and poor survival. officer fmf pin