WebbTogether, out data indicate that SLU7 is central regulator of hepatocyte identity and quiescence. The liver performs a variety of unique functions essential for the … WebbSpecifically, SLU7 has been implicated in the epigenetic remodeling of DNA, in the modulation of the transcriptional activity and in controlling protein stability. All these findings identify...
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Webb2 nov. 2024 · Finally, we discuss the implications of SLU7 in pathophysiology, with particular emphasis on the progression of liver disease and its possible role as a therapeutic target in human cancer ... Webb31 okt. 2024 · Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. ... Jimenez M, Urtasun R, Elizalde M, et al. SLU7 is a survival factor for cancer cells working as a mitotic regulator. J Hepatol 2024;66:S645-654. Zhang N, Pati D. Sororin is a master regulator of sister chromatid cohesion and separation. Cell ... opentech scanner
SLU7: A New Hub of Gene Expression Regulation-From Epigenetics to ...
WebbScale bars, 200 μm. (c) NAC treatment protected HepG2 and PLC/PRF/5 against SLU7 knockdown-induced autophagy and apoptosis, ... Resisting death is a central hallmark of cancer cells. Webbal., 2002), including cancer (Hastings and Krainer, 2001; Modrek and Lee, 2002; Stoilov et al., 2002). The splicing protein Slu7 (Frank and Guthrie, 1992) (synergistic lethal with U5 snRNA) and its human homolog hSlu7 (Chua and Reed, 1999a) have been shown to play important roles in 3′ss selection during step two of splicing. WebbExpression of SLU7 (9G8) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability … ipc energy calgary