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Impact of hypoxia on cervical cancer outcomes

Witryna14 gru 2024 · Signs and symptoms of more-advanced cervical cancer include: Vaginal bleeding after intercourse, between periods or after menopause Watery, bloody vaginal discharge that may be heavy and have a foul odor Pelvic pain or pain during intercourse When to see a doctor Witryna1 mar 2008 · The telomeric repeat amplification protocol (TRAP) assay revealed that hypoxia activated telomerase in cervical cancer ME180 cells, with peak induction at …

ALDH-1-positive cells exhibited a radioresistant phenotype ... - BMC Cancer

Witryna10 lip 2024 · Hypoxia is a typical microenvironment character in tumors with deprived adequate oxygen supply, and was shown to be a prognostic factor associated with adverse outcomes in cervical cancer... chromosome replacement therapy https://envirowash.net

Impact of hypoxia on cervical cancer outcomes Researchain

Witryna10 lis 2024 · Persistent high-risk HPV infection promotes the development of cervical intraepithelial neoplasia (CIN), which are precursor lesions for cervical cancer. 6 Clearance of the HPV infection frequently leads to regression of low-grade CIN 1/2 lesions. 6 Higher-grade CIN2+ lesions may occur if the HPV infection persists for … WitrynaStudies of tumor hypoxia involving the direct assessment of the oxygenation status have suggested worse disease-free survival for patients with hypoxic cervical cancers or … Witryna30 wrz 2024 · Despite high rates of local control, overall survival is less than 50%, largely due to distant relapse. Reducing the health burden of cervical cancer requires … chromosome research影响因子

Identification and validation of a prognostic signature related to ...

Category:Tumor hypoxia, p53, and prognosis in cervical cancers.

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Impact of hypoxia on cervical cancer outcomes

A hypoxia-related signature in lung squamous cell carcinoma

WitrynaTumor hypoxia is a common feature of the microenvironment in solid tumors, primarily due to an inadequate, and heterogeneous vascular network. It is associated with … WitrynaWe performed a PubMed literature search, using keywords related to imaging and hypoxia in cervical cancer, with a particular emphasis on studies correlating imaging …

Impact of hypoxia on cervical cancer outcomes

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Witryna15 lip 2001 · Conclusions: Advanced stage and pretreatment hemoglobin level are independent prognostic factors in cervical carcinomas. The immunohistologic … Witryna3 cze 2024 · Background: Hypoxia is a common microenvironment condition in most malignant tumors and has been shown to be associated with adverse outcomes of …

WitrynaReducing the health burden of cervical cancer requires greater individualization of treatment, identifying those at risk of relapse and progression for modified or … Witryna1 lut 2002 · Hypoxic cervical cancers are associated with poor clinical outcomes, regardless of treatment modality, which is independent of standard prognostic factors, …

Witryna14 kwi 2024 · Hypoxia has the greatest impact on patient prognosis in patients whose malignancies exhibit a “hypoxic driver” feature, and thus the efficacy of hypoxia-targeted therapies varies. Hypoxia is a significant determinant of cancer behavior and outcome, occurring in some form in most solid malignant tumors in humans. Witryna26 kwi 2024 · Tumour hypoxia is a well-known adverse factor for the outcome of radiotherapy. For cervical tumours in particular, several studies indicate large …

Witryna14 kwi 2024 · Tumor shows specific metabolic, cellular, and molecular changes in response to hypoxic environment. In cervical cancer, metastasis is a multistage …

Witrynadc.contributor.author: Datta, Anubhav: dc.contributor.author: West, Catharine M L: dc.contributor.author: O'Connor, James P B: dc.contributor.author: Choudhury, … chromosome reproductionWitryna6 kwi 2024 · Lung cancer is the leading cause of cancer deaths in the developed countries. Despite the tremendous efforts in non-small cell lung cancer (NSCLC) research and significant improvements in patient care within the last decade, the 5-year overall survival rate remains poor, resulting in 68% for patients with stage IB disease … chromosome reviewWitryna1 lut 2024 · For p53, H-score <15 and ≥15, the 5-year OS (62% and 53%), PFS (63% and 30.3%), LC (87.5% and 52%), and DMFS (79.6% and 41.6%). Conclusions: In … chromosome review worksheetWitryna1 lip 2014 · Hypoxia is a typical microenvironment character in tumors with deprived adequate oxygen supply, and was shown to be a prognostic factor associated with adverse outcomes in cervical cancer... chromosome replication phaseWitryna16 sie 2016 · Substantial data confirm the presence of hypoxia in many types of human tumors, although with considerable heterogeneity among individual tumors. Various approaches have been investigated for eliminating the hypoxic population. chromosome research journalWitrynaStudies of pretreatment tumor hypoxia involving direct assessment (polarographic oxygen tension measurements) have suggested a poor prognosis for patients with hypoxic tumors. These investigations indicate a worse disease-free survival for patients with hypoxic cancers of the uterine cervix or soft tissue sarcomas. chromosome research 影响因子Witryna3 lip 2024 · For describing a hypoxia cervical cancer risk factor model, 200 genes related to the hypoxia pathway downloaded from MSigDB for analysis. The TCGA-TPM data of cervical cancer samples were divided into high and low expression groups according to the median of gene expression and a cox analysis as based on OS (the … chromosomes 1-22