Web1. Embedded object. 2. Linked object. 3. Source file. Linked objects. When an object is linked, information can be updated if the source file is modified. Linked data is stored in the source file. The Word file, or destination file, stores only the location of the source file, and it displays a representation of the linked data. WebGraph-linked unified embedding for single-cell multi-omics data integration For more details, please check out our publication. Directory structure
Multi-omics single-cell data integration and regulatory inference …
WebOct 12, 2024 · Finally, the recently published Graph-Linked Unified Embedding (GLUE) framework (Cao and Gao, 2024) is based on the construction of a guidance graph based on prior knowledge of the … WebThis section provides detailed API documentation for all public functions and classes in scglue. scglue GLUE (Graph-Linked Unified Embedding) . Read the Docs simple water aerobics
Multi-omics single-cell data integration and regulatory …
WebMay 2, 2024 · See new Tweets. Conversation We assume that there are K different omics layers to be integrated, each with a distinct feature set \({{{\mathcal{V}}}}_k,k = 1,2, \ldots ,K\). For example, in scRNA-seq, \({\mathcal{V}}_k\) is the set of genes, while in scATAC-seq, \({{{\mathcal{V}}}}_k\) is the set of chromatin regions. The data … See more As shown in previous work31, canonical adversarial alignment amounts to minimizing a generalized form of Jensen–Shannon divergence among the cell embedding distributions of different omics layers: where … See more We applied linear dimensionality reduction using canonical methods such as PCA (for scRNA-seq) or LSI (latent semantic indexing, for scATAC … See more To handle batch effect within omics layers, we incorporate batch as a covariate of the data decoders. Assuming \(b \in \left\{ {1,2, \ldots ,B} \right\}\), is the batch index, where B is the total number of batches, the decoder … See more The integration consistency score is a measure of consistency between the integrated multi-omics data and the guidance graph. First, we jointly cluster cells from all omics layers in the aligned cell embedding … See more WebAug 22, 2024 · bioRxiv.org - the preprint server for Biology simple water clipart