WebDicetyl Phosphate. Therefore, DCP and phosphatidic acid are known as negatively charged molecules, while stearylamine (SA) and cetylpyridinium chloride are positively charged molecules that are both commonly used for preventing aggregation of niosomes. From: Strategies to Modify the Drug Release from Pharmaceutical Systems, 2015. WebSelected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as bilayer membrane additives and prepared using four different methods. A 5-fold increase in NTX entrapment efficiency (EE%) was achieved with 2%-5% mol/mol additives.
Formulation and Characterization of Drug Loaded Nonionic ... - Hindawi
WebThe inclusion of surface charge modifiers in the formulation such as dicetyl phosphate (DCP) and stearylamine (SA) to enhance drug encapsulation was also evaluated. Particle size, surface charge, and encapsulation efficiency were performed on daptomycin-hydrated proliposomes as part of physical characterization. USP type II dissolution ... WebPROTAPHOS DCP is a complex mixtures of phosphate ester of cetyl alcohol and phosphoric acid and is offered in a free acid form. PROTAPHOS DCP can be neutralized to any desired PH with basic materials such as TEA, MEA, Ammonium, Sodium or Potassium Hydroxides of which will enhance its aqueous solubility. darlenerichard195 yahoo.com
Use of niosomes for the treatment of intracellular pathogens …
WebMultilamellar liposomes consisting of dipalmitoyl phosphatidylcholine (DPPC) and dicetyl phosphate (DCP) in a molar ratio of 8:2 (DPPC:DCP = 8:2) were coated with ... WebSep 27, 2008 · In contrast, liposomes containing only DPPC are very stable at room temperature. Compositions with a high stability are those that have present SFM or STE. The latter keeps the structural bilayer at temperatures < 0°C without cryoprotectors. Both the lipids, STE and DCP, form vesicles with a higher number of lamellae. Webrespect to particle size, shape, entrapment e ciency, and in vitro characteristics. Dicetyl phosphate (DCP) was also added in the niosomal formulation. Mean particle size of niosomal formulation was found to be in the range of mto m. Niosomal formulation N 2 (:) ratio of cholesterol and surfactant displayed good entrapment e ciency ( . %). TEM ... darlene richardson obituary